Check it out, it's much easier to use and they don't charge any markup.

One thing I like about Route53 is how granular the permission can be. This lets you automate things more easily and securely.

Yeah AFAIK people use Route53 when, e.g., there is a need to automate making subdomains for customers and stuff like that.

IAM permissions are almost always a pain to get right but they can be so useful when you can create an API key with permissions to do only exactly what it needs to do.