Oh I see. But on your guid thing, people often describe entropy in terms of the set of micro states of your system (the actually physical states in your model) and the macro states (sets of microstates that are described by a collection of high-level state variables like pressure/temperature).

Physically indistinguishable stuff would have the same micro state, so yeah, they wouldn't affect entropy calculations at all, no matter what macro states you picked.

But I disagree a bit about grounding things in reality - some concepts are quite abstract and having clean examples can be helpful, before you start applying them to the mess that is our universe!