I have recently started to use uv, and you can just do "uvx tool" and it executes the tool (https://docs.astral.sh/uv/guides/tools/). Sure, the tool needs to do something to be able to be executed like that, but it seems pretty easy. And there's also a way to embed the dependencies with a comment at the top of a python script: https://docs.astral.sh/uv/guides/scripts/#running-a-script-w...

The venv created for this is ephemereal (it can not be if you want), so you don't need to keep in mind cleaning up stuff and so. Also uv is really fast in creating the venv and installing whatever is needed. Coming from using plain pip and venvs (and having pain setting up different python version interpreters for projects), and poetry just after that, I am pretty happy with the improvements.