I'm running silverblue but running my containers through distrobox. Both toolbox and distrobox are running on podman under the hood, so it's the same technology as far as I understand. However, distrobox has some interesting features relevant to this idea of development isolation. One is that it has an assemble feature[1] built-in. Where you can feed it a recipe file and it will build or rebuild containers accordingly. The other is that it allows setting a custom home directory for the container, among other host/container isolating options[2].

Perfomance wise my containers take a couple MB of rams and no perceptible CPU usage when not in use. At least as far as I can tell.

[1] https://github.com/89luca89/distrobox/blob/main/docs/usage/d...

[2] https://github.com/89luca89/distrobox/blob/main/docs/usage/d...