EUCs are great for mixed mode commute where you need to take a bus or a subway, or when you don't like keeping your expensive bike parked outside (you can roll it beside you like luggage). You can also ride it one way and Uber back, so that's convenient. Curbs, gravel, any sort of construction are a hassle - I can jump curbs just fine on my hardtail, but with EUCs you need to time the jump just right and if you mistime it you end up with the wheel rolling away and potentially a couple new scuffs on the case - not to mention the embarassment. Wrist protection is also mandatory. Knee stress also seems higher, especially with lots of curb jumping or on bad roads where you need to keep your knees bent to absorb impacts (newer suspension EUCs help with that, but they're also heavier and more expensive).

PS. oh, and it's much nicer than biking in hot weather, although I guess same is the case with e-bikes.